How to Approach Dysphagia – Lecture by Dr. Yusra Shareef
- Dr. Amin ali

- 3 days ago
- 3 min read
Welcome back, med students! Today, we’re tackling a high-yield gastroenterology topic that shows up both on the wards and in board exams: dysphagia.
When a patient says they have “trouble swallowing,” your diagnostic reasoning must kick in immediately. Dysphagia has a broad differential, ranging from harmless strictures to serious neurological conditions. Let’s break down a step-by-step clinical approach.
📹 Watch Dr. Yusra Shareef’s full lecture on Brocali
Key Points from the Lecture
Dr. Shareef emphasizes a systematic approach to dysphagia for med students:

Step 1: Clarify the Symptom — Dysphagia vs. Odynophagia
First, make sure the patient actually has dysphagia.
Dysphagia: Difficulty swallowing.
Odynophagia: Pain when swallowing.
While a patient can have both, isolating the symptom is critical:
Pill Esophagitis: Certain meds can stick and ulcerate the esophagus. Teach patients to take pills with plenty of water and stay upright for 30 minutes.
Infectious Esophagitis: Consider HIV, Candida, or CMV in immunocompromised patients.

Step 2: Localize the Lesion — Oropharyngeal vs. Esophageal
Next, identify where the swallowing problem occurs:
Oropharyngeal Dysphagia: Difficulty initiating a swallow. Patients feel the food “stuck” in the mouth or upper throat.
Esophageal Dysphagia: Swallow starts normally, but food feels stuck lower in the chest.
This distinction guides history-taking, examination, and investigations.

Step 3: Determine the Mechanism — Structural vs. Propulsive
Once location is clarified, identify whether the problem is structural (anatomical) or propulsive (motility/neurological).
1. Oropharyngeal Dysphagia
Structural Causes:
Zenker’s Diverticulum: An outpouching in the pharynx that traps food. Signs: regurgitation of undigested food (sometimes on the pillow), halitosis.
Other Causes: Cervical webs, neoplasms, or strictures from corrosive injuries.
Propulsive Causes:
Neurological disorders: stroke, Parkinson’s disease, ALS.
Neuromuscular disorders: myasthenia gravis, polymyositis, or mixed connective tissue disease.
2. Esophageal Dysphagia
Ask: “Do you have trouble swallowing solids, liquids, or both?”
Structural Causes (Solids First):
Mechanical obstruction typically starts with solids.
Progressive dysphagia to solids and eventually liquids → suspect esophageal malignancy.
Other non-malignant causes: esophageal webs, rings, peptic strictures, or chronic reflux leading to fibrosis.
Propulsive Causes (Solids + Liquids):
Difficulty with both solids and liquids points to esophageal motility disorders.
Examples: achalasia, diffuse esophageal spasm, or systemic disorders affecting esophageal muscle/nerves.

Takeaway for Med Students
Dysphagia is a common and clinically significant symptom. By approaching it systematically — identifying the type, taking a focused history, selecting appropriate investigations, and applying cause-specific management — med students can confidently handle clinical cases and excel in exams.
Why Med Students Should Use Brocali
The Brocali platform is more than just video lectures. Here’s why it’s perfect for med students preparing for clinical rotations and exams:
Structured Learning Path: No more wasted time figuring out what to study.
Arabic & English Resources: Videos, summaries, and question banks in multiple formats.
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Expert-Led Sessions: Learn from specialists like Dr. Yusra Shareef who break down complex topics into digestible steps.
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Practice Question
A 40-year-old patient presents with difficulty swallowing solids and liquids, chest discomfort, and weight loss. A barium swallow is attached for review.

Question: Which of the following is the most likely diagnosis?
Choices: A) Achalasia
B) Diffuse esophageal spasm
C) Reflux disease
D) Tumor
Answer & Explanation
Correct Answer:
A. Achalasia - Achalasia is a motility disorder of the esophagus characterized by impaired relaxation of the LES and esophageal aperistalsis. This leads to dysphagia for both liquids and solids, with liquids affected first. On barium swallow, the classic finding is a “bird’s beak” appearance at the LES. Patients may also experience chest discomfort and weight loss.
Treatment options include:
Medical: Sublingual nitroglycerin, nitrates, or calcium channel blockers
Endoscopic: Pneumatic dilation or botulinum toxin injection
Surgical: Heller myotomy for severe cases
Why the other options are incorrect:
B) Diffuse esophageal spasm: Usually presents with intermittent painful swallowing; barium shows a corkscrew pattern, not a bird’s beak.
C) Reflux disease (GERD): Causes heartburn/regurgitation, not progressive dysphagia for liquids and solids.
D) Tumor: Typically causes progressive dysphagia to solids first; LES usually relaxes normally.
Takeaway: The bird’s beak on barium swallow is pathognomonic for achalasia, a disorder of LES relaxation and loss of peristalsis causing dysphagia for both solids and liquids.
Reference:Kasper, D. L., Fauci, A. S., Hauser, S. L., Longo, D. L., Jameson, J. L., & Loscalzo, J. (2020). Diseases of the Esophagus. In Harrison’s Principles of Internal Medicine (20th ed., pp. 2213-2214). McGraw Hill.




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