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How to Approach Dysphagia – Lecture by Dr. Yusra Shareef

Welcome back, med students! Today, we’re tackling a high-yield gastroenterology topic that shows up both on the wards and in board exams: dysphagia.


When a patient says they have “trouble swallowing,” your diagnostic reasoning must kick in immediately. Dysphagia has a broad differential, ranging from harmless strictures to serious neurological conditions. Let’s break down a step-by-step clinical approach.


📹 Watch Dr. Yusra Shareef’s full lecture on Brocali



Key Points from the Lecture


Dr. Shareef emphasizes a systematic approach to dysphagia for med students:


Flowchart titled The Dysphagia Master Algorithm showing categories and causes of Oropharyngeal and Esophageal dysphagia on a white background.

Step 1: Clarify the Symptom — Dysphagia vs. Odynophagia


First, make sure the patient actually has dysphagia.

  • Dysphagia: Difficulty swallowing.

  • Odynophagia: Pain when swallowing.


While a patient can have both, isolating the symptom is critical:

  • Pill Esophagitis: Certain meds can stick and ulcerate the esophagus. Teach patients to take pills with plenty of water and stay upright for 30 minutes.

  • Infectious Esophagitis: Consider HIV, Candida, or CMV in immunocompromised patients.


Two diagrams compare dysphagia and odynophagia. Dysphagia shows swallowing mechanics; odynophagia indicates pain. Text notes differences. Colors: purple, teal.

Step 2: Localize the Lesion — Oropharyngeal vs. Esophageal


Next, identify where the swallowing problem occurs:

  • Oropharyngeal Dysphagia: Difficulty initiating a swallow. Patients feel the food “stuck” in the mouth or upper throat.

  • Esophageal Dysphagia: Swallow starts normally, but food feels stuck lower in the chest.


This distinction guides history-taking, examination, and investigations.


Silhouette of a person with digestive system diagram. Text: "The Anatomical Divide: Transfer vs. Transport." Zones: Oropharyngeal, Esophageal.

Step 3: Determine the Mechanism — Structural vs. Propulsive


Once location is clarified, identify whether the problem is structural (anatomical) or propulsive (motility/neurological).


1. Oropharyngeal Dysphagia


Structural Causes:

  • Zenker’s Diverticulum: An outpouching in the pharynx that traps food. Signs: regurgitation of undigested food (sometimes on the pillow), halitosis.

  • Other Causes: Cervical webs, neoplasms, or strictures from corrosive injuries.


Propulsive Causes:

  • Neurological disorders: stroke, Parkinson’s disease, ALS.

  • Neuromuscular disorders: myasthenia gravis, polymyositis, or mixed connective tissue disease.


2. Esophageal Dysphagia


Ask: “Do you have trouble swallowing solids, liquids, or both?”

Structural Causes (Solids First):

  • Mechanical obstruction typically starts with solids.

  • Progressive dysphagia to solids and eventually liquids → suspect esophageal malignancy.

  • Other non-malignant causes: esophageal webs, rings, peptic strictures, or chronic reflux leading to fibrosis.


Propulsive Causes (Solids + Liquids):

  • Difficulty with both solids and liquids points to esophageal motility disorders.

  • Examples: achalasia, diffuse esophageal spasm, or systemic disorders affecting esophageal muscle/nerves.


Illustration compares solids vs. solids and liquids causing obstructions. Left: steak, bread (solids). Right: steak, glass (liquids).

Takeaway for Med Students


Dysphagia is a common and clinically significant symptom. By approaching it systematically — identifying the type, taking a focused history, selecting appropriate investigations, and applying cause-specific management — med students can confidently handle clinical cases and excel in exams.


Why Med Students Should Use Brocali


The Brocali platform is more than just video lectures. Here’s why it’s perfect for med students preparing for clinical rotations and exams:

  • Structured Learning Path: No more wasted time figuring out what to study.

  • Arabic & English Resources: Videos, summaries, and question banks in multiple formats.

  • Active Recall & Practice Questions: Apply your knowledge immediately after watching lectures.

  • Expert-Led Sessions: Learn from specialists like Dr. Yusra Shareef who break down complex topics into digestible steps.



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Practice Question


A 40-year-old patient presents with difficulty swallowing solids and liquids, chest discomfort, and weight loss. A barium swallow is attached for review.


X-ray image of a human esophagus with a barium swallow, showing a narrow, elongated white contrast against dark rib shadows.











Question: Which of the following is the most likely diagnosis?

Choices: A) Achalasia

B) Diffuse esophageal spasm

C) Reflux disease

D) Tumor


Answer & Explanation


Correct Answer:

A. Achalasia - Achalasia is a motility disorder of the esophagus characterized by impaired relaxation of the LES and esophageal aperistalsis. This leads to dysphagia for both liquids and solids, with liquids affected first. On barium swallow, the classic finding is a “bird’s beak” appearance at the LES. Patients may also experience chest discomfort and weight loss.

Treatment options include:

  • Medical: Sublingual nitroglycerin, nitrates, or calcium channel blockers

  • Endoscopic: Pneumatic dilation or botulinum toxin injection

  • Surgical: Heller myotomy for severe cases


Why the other options are incorrect:

  • B) Diffuse esophageal spasm: Usually presents with intermittent painful swallowing; barium shows a corkscrew pattern, not a bird’s beak.

  • C) Reflux disease (GERD): Causes heartburn/regurgitation, not progressive dysphagia for liquids and solids.

  • D) Tumor: Typically causes progressive dysphagia to solids first; LES usually relaxes normally.


Takeaway: The bird’s beak on barium swallow is pathognomonic for achalasia, a disorder of LES relaxation and loss of peristalsis causing dysphagia for both solids and liquids.


Reference:Kasper, D. L., Fauci, A. S., Hauser, S. L., Longo, D. L., Jameson, J. L., & Loscalzo, J. (2020). Diseases of the Esophagus. In Harrison’s Principles of Internal Medicine (20th ed., pp. 2213-2214). McGraw Hill.

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